Faculty Member – Aykin-Burns
Nukhet Aykin-Burns, Ph.D.
Assistant Professor of Pharmaceutical Sciences
Member, Division of Radiation Health
E-mail address: NAykinBurns@uams.edu
Phone: 501-603 1375 (office)/501-603 1376 (lab)
- Dr. Aykin-Burns received her Ph.D. degree from the University of Missouri-Rolla (currently known as Missouri University of Science and Technology) focusing on antioxidant-based therapies in lead poisoning. She received postdoctoral training at the Free Radical and Radiation Biology Program (FRRBP), Department of Radiation Oncology at the University of Iowa.
- Dr. Aykin-Burns is Assistant Professor of Pharmaceutical Sciences at University of Arkansas for Medical Sciences (UAMS), member of the College of Pharmacy Division of Radiation Health.
- Dr. Aykin-Burns’s research focuses on reactive oxygen species (ROS), radiation induced (IR and UV) normal tissue damage and wound healing as well as polychlorinated biphenyl (PCB) induced oxidative stress.
- Secondary appointment at The University of Iowa, Human Toxicology Program
Aykin-Burns, N., Slane, B.G., Liu, A.T.Y., Owens, K.M., O’Malley, M.S., Smith, B.J., Domann, F.E., Spitz, D.R. (2011) Sensitivity to low dose/low LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondrial derived reactive oxygen species. Radiat Res 175, 150-158. PMID:21268708
Ross C., Alston, M., Bickenbach, J.R., Aykin-Burns, N. (2011) Oxygen tension changes the rate of migration of human skin keratinocytes in an age-related manner. Exp Dermatol 20:58-63. PMID:21158939
Kim, H.S., Patel, K., Muldoon-Jacobs, K., Bisht, K.S., Aykin-Burns, N., Pennington, J.D., van der Meer, R., Nguyen, P., Savage, J., Owens, K.M., Vassilopoulos, A., Ozden, O., Park, S.H., Singh, K.K., Abdulkadir, S.A., Spitz, D.R., Deng, C.X., Gius, D. (2010) SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress. Cancer Cell 17, 41-52. PMID:20129246
Zhu, Y., Kalen, A.L., Li, L., Lehmler, H.J., Robertson, L.W., Goswami, P.C., Spitz, D.R., Aykin-Burns, N. (2009) Polychlorinated-biphenyl-induced oxidative stress and cytotoxicity can be mitigated by antioxidants after exposure. Free Radic Biol Med 47, 1762-1771. PMID:19796678
Aykin-Burns, N., Ahmad, I. M., Zhu, Y., Oberley, L. and Spitz, D. R. (2009) Increased levels of superoxide and hydrogen peroxide mediate the differential susceptibility of cancer cells vs. normal cells to glucose deprivation. Biochem J 418, 29-37. PMID:18937644