UAMS.EDU

Faculty Member – Bill Gurley

Bill J. Gurley, PhD
Professor

Department of Pharmaceutical Sciences
Office: ED II, Room 6/110D
Phone: 501-686-6279
FAX: 501-686-6510
E-mail: GurleyBillyJ@uams.edu

Education & Training

Bachelor of Science Tennessee Technological University
(Pre-Pharmacy/Chemistry) June 1980

Bachelor of Science University of Tennessee, Memphis
(Pharmacy, with honors) June 1983

Doctor of Philosophy University of Tennessee, Memphis
(Pharmaceutics) December 1989

Teaching Responsibilities

Instructor and Course Coordinator (1991-present) Clinical Pharmacokinetics (PhSci. 4464), a 4 credit hour didactic course.

Instructor (2010-present) Pharmacology (PhSci 4124), a 4 credit hour didactic course.

Instructor (2014-present) Pharmacology (PhSci 4134), a 4 credit hour didactic course.

Instructor (2014-present) Pharmaceutics (PhSci 3414), a 4 credit hour didactic course.

Instructor and Course Coordinator (2003-present) Drug Interactions (PhSci. 5122), a 2 credit hour didactic course.

Instructor and Course Coordinator (1991-present) Clinical Pharmacokinetics (PhSci. 4464), a 4 credit hour didactic course.

Instructor and Course Coordinator (1994-present) Chromatographic Separations: Medical and Pharmaceutical Applications (PHSC. 5464), a 3 credit hour didactic graduate course.

Instructor (1993-present) Special Problems in Pharmaceutical Sciences (PHSC. 5262), a 3 credit hour didactic graduate course.

Research & Scholarly Interests

Mechanisms of herb-drug interactions; toxicity of multiple-component herbal dietary supplements; phytochemical modulation of drug metabolizing enzymes and drug transport proteins; influence of aging on phytochemical disposition.

Honors & Awards

2016—UAMS, Department of Pharmaceutical Sciences “Outstanding Professor” Award.

2015—Selected to serve on the United States Pharmacopeia (USP) Expert Committee on Non-botanical Dietary Supplements.

2012—Selected to serve on the Editorial Board for the journal “Phytomedicine”

2012—UAMS, Department of Pharmaceutical Sciences “Outstanding Professor” Award.

2010—Elected to serve on the United States Pharmacopeia (USP) Expert Committee on Dietary Supplements.

2010—Chair, UAMS Institutional Animal Care and Use Committee

2009—Selected to serve on the Editorial Board for the journal “Clinical Pharmacology & Therapeutics”

2008—Selected to serve as an External Advisory Committee Member for the NIH-sponsored Botanical Research Center at the Pennington Biomedical Research Center, Baton Rouge, LA.

2007—Selected to serve on the Advisory Board to the American Botanical Council

2004—UAMS, Department of Pharmaceutical Sciences “Most Outstanding Faculty Award.”

2000—UAMS, Department of Pharmaceutical Sciences “Most Outstanding Faculty Award.”

1997—Lloyd R. Thompson Memorial Award for the “Most Outstanding Professor in the UAMS Department of Pharmaceutics.”

1995—Lloyd R. Thompson Memorial Award for the “Most Outstanding Professor in the UAMS Department of Pharmaceutics.”

Memberships
American Association of Pharmaceutical Scientists, 1986 – present
American Association of Colleges of Pharmacy, 1991– present
American Association for the Advancement of Science, 1990 – present
American Society for Clinical Pharmacology and Therapeutics, 2002 – present

Publications 
Gurley, B. Dietary Supplement. Encyclopedia Britannica Online. Encyclopedia Britannica Inc., 2014. Web. August 20, 2014. (http://www.britannica.com/EBchecked /topic /162791/dietary-supplement/%20supplement.)

Gurley BJ, Steelman S, Thomas S. Multi-ingredient, caffeine-containing dietary supplements: history, safety, and efficacy. Clinical Therapeutics. 2015;37:275-301.

Gupta PK, Barone G, Gurley BJ, Fifer K, Hendrickson HP. Hydrastine pharmacokinetics and metabolism after oral administration of goldenseal (Hydrastis canadensis) to humans. Drug Metabolism & Disposition. 2015;43:534-552.

Wang X, Zhu H-J, Munoz J, Gurley BJ, Markowitz JS. An ex vivo approach to botanical-drug interactions: A proof of concept study. Journal of Ethnopharmacology. 2015;163:149-156.

Hammond D, Thano E, Bohnenberger K, McAllister M, Wannenburg T, Hsu S, Gurley B, Kim R. Ventricular tachycardia precipitated by the use of diet supplement Hydroxycut Gummies™. Hospital Pharmacy. 2015;50:615-618.

Fasinu PS, Gurley BJ, Walker LA. Clinically relevant pharmacokinetic herb-drug interactions in antiretroviral therapy. Current Drug Metabolism 2016;17:52-64.

Roe AL, Paine MF, Gurley BJ, Brouwer K, Jordan S, Griffiths J. Assessing natural product-drug interactions: an end-to-end safety framework. Regulatory Toxicology & Pharmacology 2016;76:1-6.

Chen SM, Atchley DH, Murphy MA, Gurley BJ, Kamdem LK. Impact of UGT2B17 gene deletion on the pharmacokinetics of 17-hydroexemestane in healthy volunteers. Journal of Clinical Pharmacology (in press, 2016).

Oketch HA, Giancaspro GI, Gurley BJ, Roe AL, Griffiths JC. The importance of quality specifications in safety assessments of amino acids—the cases of L-tryptophan and L-citrulline. The Journal of Nutrition (in press, 2016).

Gurley BJ, Markowitz JS, Williams DK, Barone GW. Practical considerations when designing and conducting clinical herb-drug interaction studies. International Journal of Pharmacokinetics (in press, 2016).

Curriculum Vitae