Faculty Member – Junru Wang

Junru Wang, MD, PhD.
Research Assistant Professor of Pharmaceutical Sciences

Member, Division of Radiation Health
Director of Laboratory Operations

E-mail address: wangjunru@uams.edu
Phone: 501-686-6517
Fax: 501-686-7861
Office: Cancer Institute, Room 418

  • Dr. Wang received an MD degree from Hebei Medical University, Hebei, China, a Ph.D. degree in Molecular Biology from Third Medical University, Chongqing, China, and postdoctoral training in Radiation Biology from University of Iowa, Iowa, USA
  • Dr. Wang is Director of Laboratory Operations in College of Pharmacy Division of Radiation Health
  • Dr. Wang is Research Assistant Professor of Pharmaceutical Sciences at University of Arkansas for Medical Sciences (UAMS), faculty of the College of Pharmacy Division of Radiation Health, and scientist at Central Arkansas Veterans Healthcare System (CAVHS).
  • Dr. Wang’s research focuses on cancer survivorship issues, particularly radiation-induced enteropathy, and on development of medical countermeasures against radiological/nuclear accidents or terrorism.
  • Dr. Wang has published more than 60 peer reviewed scientific articles and book chapters. She is Co-investigator in two R01s, U19 (NIH/NIAID), and HDTRA (Defense Threat Reduction Agency).

Recent Publications

Wang J, Zhang J, Kulkarni A, Wang W, Garg S, Prather P, Hauer-Jensen M: Palmitoylethanolamide regulates development of intestinal radiation injury in a mast cell-dependent manner. Dig Dis Sci. 59(11):2693-703, 2014. PMID:24848354

Wang J, Kulkarni A, Chintala M, Fink LM, Hauer-Jensen M: Inhibition of protease-activated receptor 1 ameliorates intestinal radiation mucositis in a preclinical rat model. Int J Radiat Oncol Biol Phys. 85(1):208-14, 2013. PMID:22580123

Geiger H. Pawar SA. Kerschen EJ. Nattamai KJ. Hernandez I. Liang HP. Fernandez JA. Cancelas JA. Ryan MA. Kustikova O. Schambach A. Fu Q. Wang J. Fink LM. Petersen KU. Zhou D. Griffin JH. Baum C. Weiler H. Hauer-Jensen M: Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. Nature Medicine. 18(7):1123-9, 2012. PMID:22729286

Wang J, Boerma M, Kulkarnib A, Hollenberg MD, Hauer-Jensen M: Activation of Protease Activated Receptor 2 (PAR2) by an Exogenous Agonist Exacerbates Early Radiation Injury in Rat Intestine. Int J Radiat Oncol Biol Phys, 77(4):1206–1212, 2010. PMID:20610041

Boerma M, Wang J, Burnett AF, Santin AD, Roman JJ, Hauer-Jensen M: Local administration of interleukin-11 ameliorates intestinal radiation injury. Cancer Res 2007;67:9501-9506. PMID:17909060

Wang J, Boerma M, Fu Q, Fink LM, Hauer-Jensen M: Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism. Int J Radiat Oncol Biol Phys 2007;68:1483-1490. PMID:17674978

Wang J, Hauer-Jensen M: Neuroimmune interactions in the gut: potential target for mitigating or treating intestinal radiation injury. Br J Radiol 2007:80;S41-S48. PMID:17704325