Lin Song, Ph.D.

Assistant Professor, Pharmaceutical Sciences

Phone: 501.603.1599
Office: BioMed II, Room 359-2/363-2
Email: Lsong@uams.edu

Education & Training

Ph.D. in Organic Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, P. R. China
Ph.D. in Pharmaceutical Sciences, College of Pharmacy, University of Kentucky
Postdoctoral training in pharmaceutics, College of Pharmacy, University of Kentucky

Teaching Responsibilities

PhSc 3434 – Pharmaceutics II (Pharm. D. program, course coordinator)
PhSc 5033 – Pharmaceutics for Graduate Students (course coordinator)

Research & Scholarly Interests

Development of drug delivery systems for poorly water soluble drugs, especially, lipid-based drug delivery systems such as solid lipid nanoparticles, liposomes, emulsions, and micelles

Development of drug delivery systems for cancer therapy

Physicochemical characterizations of small molecules, e.g. solubility, stability, pKa, and partition coefficient

Memberships

American Association of Pharmaceutical Scientists (AAPS)

Publications

Gujarathi S, Liu X, Song L, Hendrickson H, Zheng G. (2014). A mild and efficient AgSbF6-catalyzed synthesis of fully substituted pyrroles through a sequential propargylation/amination/cycloisomerization reaction, Tetrahedron, 70(34), 5267-5273.

Madadi NR, Penthala NR, Song L, Hendrickson HP, Crooks PA. (2014). Preparation of 4,5-disubstituted-2H-1,2,3 triazoles from (Z)-2,3-diaryl substituted acrylonitriles. Tetrahedron Letter, 55(30), 4207-4211.

Song L, Bevins R, Anderson BD. (2006). Kinetics and Mechanisms of Activation of α-Amino Acid Ester Prodrugs of Camptothecins. Journal of Medicinal Chemistry, 49(14), 4344-4355.

Horn J, Jordan SL, Song L, Roberts MJ, Anderson BD, Leggas M. (2006). Validation of an HPLC method for analysis of DB-67 and its water soluble prodrug in mouse plasma. Journal of Chromatography, B: Analytical Technologies in the Biomedical and Life Sciences, 844(1), 15-22.

Xiang T-X, Jiang Z-Q, Song L, Anderson BD. (2006). Molecular Dynamics Simulations and Experimental Studies of Binding and Mobility of 7-tert-Butyldimethylsilyl-10-hydroxycamptothecin and Its 20(S)-4-Aminobutyrate Ester in DMPC Membranes. Molecular Pharmaceutics, 3(5), 589-600.