Faculty Member – Grazyna Nowak

Grazyna Nowak, MS, PhD

Professor

Office: Biomed I, Room 238B
Phone: 501-686-6345
FAX: 501-686-6057
E-mail: NowakGrazyna@uams.edu

Education & Training

University of Poznan, Poznan, Poland (M.S. 1976, Biochemistry)
Jagiellonian University, Cracow, Poland (Ph.D. 1983; Physiology, Endocrinology)
Medical University of Aarhus, Aarhus, Denmark (Post-Doctoral Fellowship, 1983-84)
University of Georgia, Athens, GA (Post-Doctoral Fellowship, 1990-94)

Teaching Responsibilities

Pharm.D. Curriculum
Biological and Cellular Chemistry (PhSc7102)

Graduate Program
Medicinal Chemistry (PhSci 5013)

Research & Scholarly Interests

My research is focused on investigating the mechanisms that regulate renal cell injury, regeneration and repair following injury induced by ischemia/reperfusion, hypoxia and nephrotoxicants. Primary focus of these studies is mitochondrial function and its regulation by protein kinases during injury and repair and how ischemia/reperfusion, drugs and xenobiotics alter this regulation. Other projects include investigation of the mechanisms of apoptosis in renal cells. In vivo model of renal ischemia/reperfusion and in vitro model of primary cultures of kidney cells are utilized to determine signal transduction pathways and protein kinases that play a role in the regeneration and repair of mitochondrial and transport functions. These research projects utilize transgenic animals and a variety of techniques including molecular biology techniques, proteomics, histology, fluorescent imaging, flow cytometry, and mitochondrial and biochemical assays. The goal of these studies is to develop new therapeutic strategies that decrease injury or accelerate recovery from ischemia/reperfusion- and nephrotoxicant-induced acute kidney injury.

Honors & Awards

2003-2006  Toxicology Letters; Editorial Board, Member
2005              NIH/NIDDK Special Emphasis Panel Study Section, Reviewer
2006              NIH/NIDDK Loan Repayment Program, Special Emphasis Panel Study Section, Reviewer
2006-present Journal of Pharmacology and Experimental Therapeutics; Editorial Board, Member
2007              NIH/NIDDK, Pathobiology of Kidney Disease (PBKD) Study Section, ad hoc Reviewer
2007              NIH/NIDDK Special Emphasis Panel Study Section, Reviewer
2007              Outstanding Online and Blended Course Award, Arkansas Distance Learning Association (ARDLA)
2007              Mentor Award, Graduate School at the University of Arkansas for Medical Sciences
2009              SoftChalk Lesson Challenge, First Honorable Mention
2012              UAMS Educational Technology Excellence Award
2013 – present American Journal of Physiology Renal Physiology, Editorial Board, Member

Memberships

American Society of Physiology
American Society of Nephrology
American Association of Colleges of Pharmacy

Publications