Using modern analytical instrumentation (e.g., LC-MS, GC-MS), the Bioanalytical Core offers high-throughput analytical services for determining diagnostic amino acids and their precursors or metabolic products. Available biomarkers include citrulline and tetrahydrobiopterin. Determination of other small molecules is possible, but fees will be assessed for the cost of method validation. The Bioanalytical Core can provide analysis of pharmacokinetic samples and subsequent determination of pharmacokinetic parameters. The Bioanalytical Core, in support of preclinical drug development or Phase 1 clinical trials and gathered in compliance with 501(a) (2)(B) of the FD&C Act, can provide bioanalytical data for Investigational New Drug (IND) applications.
Howard Hendrickson, PhD | (501) 603-1547
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Sarah Phillips, PhD | Sphillips2@uams.edu