Experimental Radiation Core

The Experimental Radiation Core maintains and operates equipment and facilities to deliver ionizing radiation for research use. The core can deliver X- and γ-rays at a broad range of dose rates and radiation field sizes for a variety of purposes, such as irradiation of cell cultures, animal whole body irradiation, irradiation of animal tumor models or other (image guided) partial-body irradiation. In addition, the core has two strontium-90 sources for small-field superficial exposures with β-radiation.

Core Services

  • Maintenance of radiation equipment and radiation dosimetry
  • Assistance in design and development of new animal and cell culture radiation models
  • Assistance and training in whole body or localized irradiation of animal models
  • Assistance and training in radiation exposure of cell cultures

Equipment and Facilities

  • Mark 1 Model 68A (J.L. Shepherd) cesium source irradiator. This irradiator can be used for animal whole body/partial body and cell culture exposures to γ-rays.
  • Model 81-8 (J.L. Shepherd) cesium source irradiator. This irradiator can be used for chronic exposure of animals to low-dose rate γ-rays.
  • Seifert Isovolt 320 X-ray generator. This X-ray machine can be used for localized irradiation.
  • Small Animal Radiation Research Platform (SARRP, Xstrahl). This system incorporates cone beam computed tomography (CBCT) imaging and radiation planning software to deliver precise X-ray beams to anatomical targets, similar to clinical radiation therapy.
  • Strontium-90 β-sources. These sources can be used for irradiation of superficial targets such as skin while minimizing exposure of underlying tissues.

Pricing and Scheduling

    • Shepherd Mark 1 model 68A cesium source irradiator: $125 per hour
    • Shepherd Mark 1 model 68A cesium source irradiator (select trained users who do not need assistance from core staff): $85 per hour
    • SARRP (operated by core staff only): $130 per hour

    Each usage will be billed for at least 1 hour.

For scheduling, please contact:

Marjan Boerma mboerma@uams.edu, office: 501-686-6599

Kim Krager kjkrager@uams.edu

SARRP:

This irradiator incorporates CBCT imaging and radiation planning software to deliver precise X-ray beams to anatomical targets. The target can be exposed through a single beam, multiple beams, or arcs, matching clinical radiation therapy techniques.

Chronic irradiation facility:

A chronic irradiation facility was built in 2018, using a cesium source that is capable of scattering radiation in all direction at pre-set dose rates. The configuration in the figure will lead to a dose rate of approximately 0.1 cGy/hour. Animals can be housed around the source and irradiated continuously for hours up to several months.